A blockbuster Premier League clash awaits as Liverpool host Arsenal at Anfield in a match that could have significant implications for the title race. Liverpool, fresh off clinching the 2024-25 Premier League title, are riding high under Arne Slot, with their attacking prowess led by Mohamed Salah in scintillating form. Arsenal, managed by Mikel Arteta, are battling to secure a strong position in the top four while nursing injury concerns and a recent Champions League semi-final exit against PSG. With both teams boasting rich histories and recent competitive encounters, this fixture promises goals, drama, and tactical intrigue.
Prediction
Liverpool enter this match as favorites, given their dominant form and home advantage at Anfield. The Reds have lost just once in their last 12 matches across all competitions, showcasing a balanced squad with a lethal attack and the league’s best defensive record, conceding only 0.6 goals per game on average. Mohamed Salah, the Premier League’s top scorer with 28 goals and 18 assists, remains a constant threat, while Luis Diaz and Darwin Nunez add dynamism to the frontline.
Arsenal, despite their resilience, are hampered by injuries to key players like Gabriel Magalhaes, Gabriel Jesus, and Kai Havertz, which could weaken their defensive and attacking output. The Gunners have struggled to sustain their title challenge this season, sitting second but vulnerable to slipping further with Manchester City close behind. While Arsenal’s set-piece prowess and home form have been impressive, their away record against top sides is less convincing. Expect Liverpool to exploit Arsenal’s depleted squad, with a predicted 2-1 victory for the hosts in a tightly contested match.
Head-to-head
The rivalry between Liverpool and Arsenal is one of the Premier League’s most storied, with 242 matches played across all competitions. Liverpool hold a slight edge historically, winning 95 games to Arsenal’s 83, with 64 draws. In recent years, the fixtures have been closely fought, often producing high-scoring affairs. In their last 10 meetings, Liverpool have won four, Arsenal one, and five have ended in draws, with an average of 3.33 goals per game.
The most recent clash on October 27, 2024, at the Emirates ended in a 2-2 draw, highlighting the fine margins between these sides. Arsenal’s last league win at Anfield was in 2020, a 2-1 victory, but Liverpool have dominated at home otherwise, including a 2-0 FA Cup win in January 2024. Arsenal’s unbeaten run in their last four Premier League games against Liverpool (two wins, two draws) adds intrigue, but Liverpool’s current form suggests they could tilt the balance in their favor.
Possible lineups
Liverpool’s squad is nearing full strength, with key players like Ibrahima Konate, Andrew Robertson, Ryan Gravenberch, Alexis Mac Allister, Dominik Szoboszlai, and Luis Diaz expected to start. However, a post on X suggests Trent Alexander-Arnold might be dropped, potentially seeing Conor Bradley slot in at right-back. Alisson Becker is likely to return in goal, with Harvey Elliott and Diogo Jota still sidelined. A possible Liverpool lineup is: Alisson; Bradley, Konate, Van Dijk, Robertson; Gravenberch, Mac Allister, Jones; Salah, Nunez, Diaz.
Arsenal face significant injury challenges, with Gabriel Magalhaes, Gabriel Jesus, Kai Havertz, and Takehiro Tomiyasu ruled out, and Riccardo Calafiori also doubtful. William Saliba will anchor the defense alongside Jakub Kiwior or Ben White, while Bukayo Saka, if fit, will be crucial in attack. Mikel Arteta may opt for a cautious setup, with a possible lineup: Raya; White, Saliba, Kiwior, Zinchenko; Odegaard, Rice, Merino; Saka, Trossard, Martinelli. These lineups reflect the latest team news and tactical preferences, though Arteta might rotate after a midweek Champions League match.
Betting tips
Given the attacking talent on both sides and their recent head-to-head trends, betting on both teams to score (BTTS) at odds of around 1.65 is a strong option, as both teams have found the net in six of their last seven competitive meetings. Mohamed Salah’s exceptional form makes him a prime candidate for an anytime goalscorer bet, with odds typically around 1.80, given his 28 goals this season and history of performing well against Arsenal.
For a riskier but potentially rewarding bet, a correct score of 2-1 to Liverpool offers value at approximately 8.00, aligning with predictions of a close game. Additionally, considering Arsenal’s reliance on set pieces and Liverpool’s attacking depth, over 2.5 goals at odds of 1.65 could be a shrewd choice, as their recent encounters have averaged 2.8 goals. Punters should monitor lineup confirmations, as Arsenal’s injury list could impact their defensive stability, making Liverpool’s attacking options even more appealing for goal-related bets.

